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AbstractBACKGROUND: Sepsis is a dangerous condition that threatens life because of immune system dysregulation causedby an infection resulting in organ failure. One of the most common resistant strain bacteria that can cause sepsis isMethicillin-resistant Staphylococcus aureus (MRSA). Vancomycin is the first-line therapy for treating sepsis infectioncaused by MRSA, but recently there have been some MRSA … Read more

AbstractBackground: Previously treated tuberculosis (TB) patients are a widely reported risk factor for multidrug-resistanttuberculosis. Identifying patients’ problems during treatment is necessary to control TB, especially in a high-burdensetting. We therefore explored barriers to successful TB treatment from the patients’ perspective, aiming to identifypotential patient-centred care strategies to improve TB treatment outcome in Indonesia.Methods: A qualitative … Read more

Abstract BACKGROUND: Hyperglycemia in diabetes increases oxidative stress in the body. It causes optic nerve damage and the risk of glaucoma. AIM: In this study, we evaluated and analyzed the effect of propolis ethanol extract on the repair of optic nerve damage in a rat model for diabetes mellitus (DM). STUDY DESIGN: Laboratory experimental using … Read more

Abstract Objectives: The goal of this study was to compare cost-effectiveness of sacubitril/valsartan with angiotensin-converting enzyme (ACE) inhibitors for treating chronic heart failure patients with reduced ejection fraction (HFrEF) from the published articles and explore the methodology applied in the studies. Methods: Systematic research was conducted in February 2021 using PubMed, Cochrane, and EBSCO. A … Read more

Abstract Quality of life (QoL) is a broader concept than merely measuring morbidity and mortality. The quality of life of the child is an important factor in determining the human resources (HR) in the future and requires serious attention. District worthy of children is a comprehensive structure based on the study that precede-proceed model principle … Read more

ABSTRACTIn developing countries, millions of women of reproductive age do not use contraception, while research on factorsrelated to contraceptive use behavior are still lacking. The study aimed to identify the factors relate to the behaviorof contraceptive use. A cross-sectional study design was conducted from January to March 2020 in Bantul District,Yogyakarta Province, Indonesia. Data were … Read more

Abstract BACKGROUND: Cisplatin is one of the most potent chemotherapy drugs to treat various types of cancer, however the use of cisplatin has some the adverse effect, such as the increase of oxidative stress and inflammation by malondialdehyde (MDA) and nuclear factor kappa B (NF-kB) activation. Since the dosing of cisplatin is critical, we observed … Read more